Zevalin (Ibritumomab Tiuxetan) Injection

General Information

Zevalin (Ibritumomab Tiuxetan) Injection is used along with rituximab. It is indicated for the treatment of a certain type of cancer. It is called B-cell non-Hodgkin’s lymphoma. It is a type of cancer that originates in your lymphatic system. In this type of disease, the tumors develop from lymphocytes which are a type of white blood cell.

How does Zevalin (Ibritumomab Tiuxetan) Injection work?

Zevalin (Ibritumomab Tiuxetan) Injection has been designed to target an antigen. It is present on the surface of all B lymphocytes. When this drug is radiolabelled, the radioactive element yttrium 90 is attached to this drug. When the radio-labeled medicine is injected into the patient, the monoclonal antibody carries the radioactivity to the target CD20 antigen on the B cells. Once the antibody has bound to the antigen, the radiation can act locally. It also destroys the lymphoma B cells.

Why use Zevalin (Ibritumomab Tiuxetan) Injection?

Zevalin contains an active ingredient of Ibritumomab. It is a monoclonal antibody. A monoclonal antibody is a type of protein that has been designed to recognize and bind to a specific structure called an antigen. That is specifically found in certain cells in the body. This product comes as a clear, sterile, and preservative-free solution that may have a translucent particle. In 2 ml of 0.9% sodium chloride, each single-use vial includes 3.2 mg of Ibritumomab Tiuxetan. The Food and Drug Administration (FDA) has already approved this prescription.

How to use Zevalin (Ibritumomab Tiuxetan) Injection?

The dosage is based on your medical condition and response. It is important to take it exactly as it is prescribed. Do not take more than or more often than the prescription.

This medication is to be given by injection into a vein by a doctor or healthcare professional.

What are the side-effects of Zevalin (Ibritumomab Tiuxetan) Injection?

  • Vomiting
  • Nausea
  • Stomach pain
  • Diarrhea
  • Dizziness
  • Upset cough
  • Loss of appetite
  • Flushing
  • Joint pain
  • Anxiety
  • Tiredness
  • Fever
  • Throat weakness
  • Inflammation of the nose

If these side effects persist or worsen, call your doctor right away.

Warnings and Precautions

  • Before taking this medicine, tell your doctor if you are allergic to it. This drug may have an inactive substance that causes an allergic reaction.
  • Do not drive or do any activity that needs your alertness. This medication may make you feel dizzy.
  • Wash your hands well to prevent the spread of infections.
  • If you are pregnant or breastfeeding women, consult your doctor first.