Where is Ticagrelor used?

Ticagrelor is an antiplatelet drug that is used to help prevent heart attack and stroke in people with heart problems (unstable angina). This may also be used to prevent blood clots after certain heart surgeries. Ticagrelor blocks platelets from sticking together and prevents them from forming harmful clots.

How does Ticagrelor work?

Ticagrelor works by preventing the action of adenosine diphosphate (ADP). ADP is one of the chemicals in the body that causes platelets to clump together and start the process of blood clotting. This drug binds to a specific area on the platelets known as the P2Y12 receptors. This is thought to prevent ADP from activating the platelets and making them clump together. This decreases the likelihood of clots forming in the blood. A blood clot that forms inside the blood vessels is known as thrombosis and can be dangerous. It can cause a blockage that cuts off the blood supply to an organ. A blockage in the arteries supplying blood to the heart or brain can cause a heart attack or stroke. 

How is Ticagrelor taken?

Ticagrelor is to be taken by mouth usually twice a day. You may take each dose with or without a meal. If you have trouble swallowing the medicine, you may crush it. Mix the crushed medicine with water in a glass, then drink the mixture right away. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not take this drug more often or for longer than prescribed. Your condition will not improve any faster and your risk of side effects will increase. It is important to continue taking this medication even if you feel well.

What are the possible side effects of Ticagrelor?

  • Fatigue
  • Back pain
  • Diarrhea
  • Nausea
  • Cough
  • Dizziness
  • Headache

What are the precautions in taking Ticagrelor?

  • Ticagrelor is used with caution in people with increased risk of bleeding, who have recently had bleeding in the gut, taking other medicines that increase the risk of bleeding, who experience fainting related to a slow heart rate, or history of asthma.
  • This is not recommended for use in people with any active bleeding, who have recently had bleeding inside the skull, who have moderate to severely decrease liver function, or for people having kidney dialysis.
  • This medicine may lessen your ability to drive or operate machinery safely. Do not operate machinery or drive until you know how this medicine affects you and you are sure it won’t affect your performance.
  • Let your doctor know if you ever had an allergic reaction to this drug. Tell also if you have any allergies. This may have an ingredient that causes an allergic reaction.
  • Certain medicines should not be used during breastfeeding or pregnancy. However, other medicines may be safely used in breastfeeding or pregnancy providing the benefits to the mother outweighs the risks to the unborn baby. Don’t forget to inform your doctor if you are pregnant or have plans to become pregnant, before using any medication.