What condition does Perampanel treat?

Perampanel is an oral medication used for the treatment of certain types of seizures such as focal and generalized tonic-clonic seizures. A focal tonic-clonic seizure starts in a limited area on one side of the brain. It spreads to involve both sides. Generalized tonic-clonic seizure starts on both sides of the brain.

This prescription is used where someone has repeated fits or seizures. It has been given by your doctor to lessen the number of seizures that you have.

Perampanel belongs to the group of medicines called anti-epileptics. This comes as a tablet for oral use. This was approved by the Food and Drug Administration (FDA).

How does Perampanel work?

Perampanel works by calming the electrical activity in the brain. It inhibits epileptic fits by preventing excessive electrical activity in the brain. It blocks the action of glutamate, which is a neurotransmitter found in nerve cells. Neurotransmitters are chemicals that are stored in nerve cells. It is also involved in transmitting messages between the nerve cells.

This medication decreases the ability of glutamate to excite the nerve cells. It is by blocking glutamate receptors on the nerve cells in the brain. This is thought to help stabilize the electrical activity in the brain which prevents epileptic fits.

What is the recommended dosage for Perampanel?

The dosage depends on your medical condition and response to the treatment. Remember to take it exactly as it is prescribed. Do not take it more than the prescription to avoid some complications.

This medicine is usually taken once a day at bedtime. Each dose is to be taken by mouth with a full glass of water. Remember to take it at the same time every day. To lessen your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

What are the side effects of Perampanel?

  • Sleepiness
  • Dizziness
  • Tiredness
  • Drowsiness
  • Headache
  • Fatigue
  • Irritability
  • Joint pain
  • Weight gain
  • Back pain
  • Nausea
  • Problems maintaining balance

What are the precautions in taking Perampanel?

  • Do not suddenly stop taking this medication without consulting your doctor.
  • For people with a history of severe kidney or liver problems or on hemodialysis for kidney problems, this medicine should not be taken.
  • If you are taking medications such as St. John’s Wort or Rifampin, it is important to consult your doctor first before having a dose of this medication.
  • Sometimes one kind of drug changes the way another kind of medication works in the body. This might happen with prescription and non-prescription medicines, vitamins, herbal products, and some foods. Tell your health care provider any time a new medication is given to you or if you take other products or substances.
  • Let your doctor know if you are allergic to it. This may have an inactive ingredient that causes an allergic reaction.
  • Contact your health care provider before stopping any seizure medication. This could lead to worsening seizures and mood.
  • Keep this in a dry and clean place to avoid some contaminations.