Ogen (Estropipate)

General Information

Ogen (Estropipate) is used by women to help reduce symptoms of menopause like vaginal dryness and hot flashes. Menopause is a normal part of aging that frequently happens between 45-55 years of age, as a woman’s estrogen levels decline. These symptoms are caused by the body making less estrogen. Certain estrogen products may also be used by women after menopause. It will help prevent bone loss or osteoporosis. 

How does Ogen (Estropipate) work?

Ogen (Estropipate) acts by regulating the transcription of a limited number of genes. Estrogens diffuse through cell membranes and distribute themselves throughout the cell. It also binds to and activates the nuclear estrogen receptor. It is a DNA-binding protein which is found in estrogen-responsive tissues. The activated estrogen receptor binds to specific DNA sequences or hormone-response elements. It enhances the transcription of adjacent genes and in turn, leads to the observed effects. Estrogen receptors have been identified in tissues of the reproductive tract, pituitary, breast, liver, hypothalamus, and bone of women. 

Why use Ogen (Estropipate)?

Ogen (Estropipate) belongs to the group of medications known as estrogen replacement therapy. It is a hormone that is produced by ovaries. This product contains Estropipate as an active ingredient and it is a type of estrogen. This is available as tablets for oral use that has the strengths of 0.75mg, 1.5mg, and 3mg. The (Food and Drug Administration) FDA approved this medication. 

How to use Ogen (Estropipate)?

The recommended dosage for this drug is based on medical condition and response.

This drug is to be taken by mouth with a full glass of water. You may take it with or without food. You may also take it with food right after a meal to prevent stomach upset.

Take it at the same time each day. Do not take it more than the prescription of your doctor.

What are the side-effects of Ogen (Estropipate)?

  • Nausea
  • Stomach upset
  • Loss of appetite
  • Vomiting
  • Breast tenderness or swelling
  • Bloating
  • Weight changes
  • Migraine or headache
  • Decreased sex drive
  • Acne or skin color changes
  • Dizziness
  • Changes in your menstrual periods
  • Swelling of your ankles or feet

Warnings and Precautions

  • This is not recommended to use in pregnant women. If you are breastfeeding, talk to your doctor first.
  • Tell your doctor if you are allergic to this drug or if you have any allergies. This may contain an inactive ingredient that may cause an allergic reaction.
  • Inform your doctor about the medical history you have had as well as your current medications.