Mavyret (Glecaprevir and Pibrentasvir)

General Information

Mavyret (Glecaprevir and Pibrentasvir) is used to treat viral infections of the liver and chronic hepatitis C virus (HCV).

This medication lessens the amount of hepatitis C virus in your body. Which it helps your immune system fight the infection and helps your liver recover. Chronic hepatitis C can cause serious liver problems such as scarring or also called cirrhosis. It may also cause liver cancer.

How does Mavyret (Glecaprevir and Pibrentasvir) work?

Mavyret (Glecaprevir and Pibrentasvir) is inhibitor Glecaprevir which is a viral enzyme. It is needed for the proteolytic cleavage of the HCV encoded polyprotein into mature forms of different proteins. These proteins are essential for viral replication. This drug disrupts the intracellular processes of the viral life cycle. It is through inhibiting its activity of cleaving downstream junctions of HCV polypeptide and proteolytic processing of mature structural proteins.

Why use Mavyret (Glecaprevir and Pibrentasvir)?

Mavyret is a fixed-dose combination of Glecaprevir and Pibrentasvir. Those are HCV NS3/4A protease inhibitor and NS5A inhibitor. It is supplied as a tablet for oral use. It is a combined product that has Pibrentasvir 40 mg and Glecaprevir 100 mg in each tablet. The U.S. Food and Drug Administration (FDA) has already approved this drug in 2017.

How to use Mavyret (Glecaprevir and Pibrentasvir)?

This medication is to be taken by mouth usually once each day. It is to be taken with food as directed by your doctor. The dosage is based on your medical condition and response to it.

Remember to take it at the same time every day. It is important to take it exactly as it is prescribed medically. Continue to take it for the full length of time prescribed even if symptoms disappear after a short time. Stopping the medication too early may result in a return of the infection.

What are the side-effects of Mavyret (Glecaprevir and Pibrentasvir)?

  • Fatigue
  • Headache
  • Diarrhea
  • Nausea
  • Lack of energy
  • Weakness

Call for medical help if there are signs of an allergic reaction:

  • Trouble breathing
  • Hives
  • Swelling of your lips, face, throat, or tongue

Warnings and Precautions

  • Before using this medication, tell your doctor if you have any medical history or current medications.
  • Let your doctor know if you have any allergies. This drug may have an inactive ingredient that causes an allergic reaction.
  • This may not be prescribed for pregnant or breastfeeding women. before using, consult your doctor first.
  • Keep this far from the reach of children.