General Information

Leflunomide is indicated for the treatment of rheumatoid arthritis. It is a condition in which the body’s defense system or immune system fails to recognize the body itself. It also attacks the healthy tissues around the joints. This medication helps to lessen joint pain, damage, and swelling. Leflunomide will also help you to move better.

How does Leflunomide work?

Rheumatoid arthritis occurs when your immune system becomes overactive. That it attacks some parts of your body such as your joints. Leflunomide works by blocking the part of your immune system. This also blocks some proteins in your body that causes inflammation.

Why use Leflunomide?

Leflunomide is a prescription approved by the Food and Drug Administration (FDA). This is a nonbiologic disease-modifying antirheumatic drug (DMARD). This is also a pyrimidine synthesis inhibitor. Leflunomide starts to work with positive effects at 4 to 8 weeks of treatment. This has the maximum benefit at 3 to 6 months. Leflunomide suppresses the immune system to lessen the pain and swelling in rheumatoid arthritis. This is available for oral use with the strengths of 10 mg, 20 mg, and 100 mg.

How to use Leflunomide?

The dosage is based on your medical condition, age, weight, and response to it. It is important that you take this medication exactly as it is prescribed. Do not take more often more than the prescribed dosage.

Leflunomide is to be taken by mouth usually once a day. You may take each dose with or without a meal. Swallow the medicine as a whole with a full glass of water. For the best benefit, take it regularly. Remember to take the medicine at the same time each day. Tell your doctor if your condition persists or gets worse.

What are the side effects of Leflunomide?

  • Nausea
  • Diarrhea
  • Loss of appetite
  • Stomach pain
  • Headache
  • Weight loss
  • Back pain
  • Dizziness
  • Runny or stuffy nose
  • Numbness or tingling
  • Itching or skin rash
  • Cold symptoms

Warnings and Precautions

  • Tell your doctor if you have liver or kidney disease before taking this medication.
  • This is not recommended if you have a weak immune system or serious infections.
  • Let your doctor know if you have any medical history, current medications, or allergies.
  • Do not have vaccinations or immunizations without the consent of your doctor.
  • During pregnancy, this drug is not recommended. If you are breastfeeding women, consult your doctor first.
  • Keep this at a dry and clean place away from heat and moisture.