Where is Ixazomib used?

Ixazomib is a drug treatment used for multiple myeloma. This medicine stops or slows the growth of the cells that causes cancer. This is usually used along with other medications in people who have received at least one prior treatment. Ixazomib belongs to a family of medicines called proteasome inhibitors. The U.S. Food and Drug Administration has already approved this prescription. 

How does Ixazomib work?

Both normal and cancer cells have proteasomes, enzyme complexes that break down impaired and unsolicited proteins into lesser components. These lesser components are then used to make new proteins needed by the cell. Proteasomes can be alleged as critical to the cell’s recycling of proteins. Myeloma cells are mainly subtle to proteasome inhibition. Once their protein recycling system is shut down, myeloma cells die. 

How is Ixazomib taken?

The recommended dosage depends on your medical condition, lab tests, and response to treatment. Take this medicine by mouth at least 1 hour before or 2 hours after a meal. This is usually taken once a week for at least 3 weeks. As directed by your doctor, the medication is stopped for 1 week. This is one cycle of treatment. Continue taking the medicine this way as directed. Swallow the medication as a whole with water. If you vomit after taking a dosage, do not take another at that time. Take your next dosage at a fixed time.

Do not use this drug more frequently or for longer than recommended and do not increase your dose. Your condition will not recover any sooner, and it will increase your risk of side effects. Since this medicine can be absorbed through the skin and may harm an unborn baby. For this reason, women who may become pregnant or who are pregnant should not handle this medicine.

What are the possible side effects of Ixazomib?

  • Diarrhea
  • Vomiting
  • Nausea
  • Constipation
  • Dry eyes
  • Blurred vision
  • Eye itching, redness, or discharge

Individuals using this medicine may have serious side effects. Nonetheless, your doctor has recommended this medicine because they have known that the benefit to you is greater than the risk of side effects.

What are the precautions in taking Ixazomib?

  • This medicine can frequently cause a rash that is usually not serious. Nevertheless, you might not be capable to tell it that can be a sign of a severe reaction. Call for medical help right away if you develop any rash.
  • This medicine can rarely cause damage to small blood vessels or serious blood clots in your body, especially in the brain or kidney. Get medical help right away if you develop symptoms such as a change in the amount of urine or unusual tiredness.
  • This medicine may cause blurred vision. Do not do any activity that needs a clear vision, drive, or use machinery until you are certain you can do such activities safely. 
  • Inform your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while taking this medication. 
  • Consult your doctor before breastfeeding.