Isonarif (Rifampin and Isoniazid)

General Information

Isonarif (Rifampin and Isoniazid) is used for tuberculosis (TB). It is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs. They can also damage other parts of the body. It spreads through the air when a person with TB of the lungs or throat sneezes, coughs, or talks. This medication may help to stop the growth of the bacteria.

How does Isonarif (Rifampin and Isoniazid) work?

Isonarif (Rifampin and Isoniazid) works by killing the bacteria that causes the disease. It is thought to prevent the tuberculosis bacteria from creating substances called mycolic acids. These are needed to form the cell walls of the bacteria. It may also be by combining with an enzyme that interferes with the cell metabolism of the bacteria. As a result, a disruption in its metabolism and without a cell wall, the bacteria will die.

Why use Isonarif (Rifampin and Isoniazid)?

Isonarif is a combined medication of Rifampin and Isoniazid. Both drugs are in the class of antibiotics. It is supplied as capsules for oral use. Each capsule has 300 mg of Rifampin which is a semisynthetic antibiotic derivative of rifamycin B. It also contains 150 mg of Isoniazid which is the hydrazide of isonicotinic. The medicines that this product contains exist as colorless or white crystals. The Food and Drug Administration (FDA) has already approved this prescription.

How to use Isonarif (Rifampin and Isoniazid)?

Isonarif (Rifampin and Isoniazid) is to be taken by mouth with a full glass of water. It is usually taken an hour before or 2 hours after a meal. If you are taking antacids, take this medication at least an hour before the antacid.

The dosage is based on your condition and response. Remember to take it at the same time and in the same way every day. Take this antibiotic at evenly spaced times for the best effects.

What are the side-effects of Isonarif (Rifampin and Isoniazid)?

  • Vomiting
  • Nausea
  • Heartburn
  • Upset stomach
  • Dizziness
  • Headache
  • Drowsiness
  • Dizziness
  • Gas
  • Diarrhea
  • Trouble sleeping
  • Changes in the color of urine, saliva, sweat, or tears

Warnings and Precautions

  • Inform your doctor if you have any allergies before taking this prescription.
  • Tell also to your doctor if you have any medical history or current medications.
  • While taking this drug, avoid alcoholic beverages. Alcohol may increase the risk of liver disease.
  • Do not have any vaccinations or immunizations while having this treatment. This product may cause live bacterial vaccines.
  • If you are pregnant or breastfeeding women, consult your doctor first.