Efalizumab

Where is Efalizumab used?

Efalizumab is used to treat moderate to severe plaque psoriasis. This is a type of medication called a monoclonal antibody. Efalizumab suppresses the part of the immune system and modifying the process of inflammation. It is made to target and destroy certain cells in the body that helps protect healthy cells from damage. The U.S. Food and Drug Administration (FDA) has already approved this prescription.

How does Efalizumab work?

Efalizumab is a suppressing part of the immune system and modifying the process of inflammation. Monoclonal antibodies are manufactured antibodies that are specifically designed to recognize and bind to unique proteins in the body. This medication works by binding to a particular protein on the surface of lymphocyte function-associated antigen-1 (LFA-1). By binding to the proteins, this drug prevents a cascade of immunologic reactions that may lead to inflammatory responses in the dermis and epidermis layers of the skin. In plaque psoriasis, this medication thickened scaly plaques of the skin and decreases skin inflammation.

The effect of this medication may reach after 1 to 2 days after subcutaneous administration.

How is Efalizumab used?

  • Efalizumab is given by subcutaneous injection that is only to be injected once a week or as directed by your doctor.
  • Do not mix the medicine ahead of time for later use. Use this medicine right away or within 8 hours after you mix it.
  • Mix the medicine as instructed by your doctor.
  • The recommended dosage is based on your medical condition and response to the treatment.  
  • Clean the injection site with rubbing alcohol before injecting each dose.
  • The injection site should be rotated each time you inject a dose.
  • Consult your doctor if your condition does not improve or if it gets worse.

What are the possible side effects of Efalizumab?

Common side effects:

  • Muscle pain
  • Headache
  • Vomiting
  • Nausea
  • Back pain
  • Joint pain
  • Stiffness

Tell your doctor right away if you have these serious side effects:

  • Chills
  • Fever
  • Mouth sores
  • Flu symptoms
  • Tenderness
  • Skin redness

What are the precautions in taking Efalizumab?

  • If your weight changes, contact your doctor immediately. Your dose may need to be adjusted.
  • Before you receive any medical or dental procedures, let your doctor know that you are taking Efalizumab.
  • While you are having this treatment, do not receive any immunization or vaccinations without the permission of your doctor.
  • Do not share this with others even if they have the same symptom as yours.
  • This is not recommended for use in children and adolescents under 18 years of age. The effectiveness and safety have not yet been confirmed.
  • If you become pregnant while you are taking Efalizumab or within 6 weeks after you stop taking this drug, call your doctor right away. You may need to discuss the benefits and risks of using this drug while you are pregnant.
  • Do not breastfeed while taking this medication.
  • Before using this, tell your doctor if you ever had an allergic reaction to this drug.
  • If there happened to be any signs of an overdose, call for medical help immediately.