What condition does Droxidopa treat?

Droxidopa is to treat symptoms of low blood pressure when standing. It is caused by neurogenic orthostatic hypotension – NOH. This prescription can decrease the signs of low blood pressure when standing. It is also known as orthostatic hypotension like light-headedness, dizziness, or the feeling that you are about to blackout.

This medicine is used in people whose daily accomplishments are severely affected by this condition. This may also be taken even after other treatments are used like water bolus or support stockings.

Droxidopa is a man-made amino acid precursor of Norepinephrine. It makes the blood vessels narrower which increases blood pressure. This medication is supplied as a capsule for oral administration. The Food and Drug Administration (FDA) has already approved this medication.

How does Droxidopa work?

Droxidopa is a synthetic amino acid analog that is openly metabolized to norepinephrine. It is by dopa-decarboxylase which is broadly distributed throughout the body. This medication is believed to exert its effects through norepinephrine. It does not exert an effect through the parent molecule or other metabolites. Norepinephrine raises blood pressure by inducing peripheral arterial and venous vasoconstriction.

What is the recommended dosage of Droxidopa?

The recommended dosage is based on your medical condition.

This medicine is usually taken 3 times, morning, midday, and late afternoon. It is to be taken by mouth with a full glass of water. You may take each dose with or without food. Swallow it as a whole. This is taken in daytime hours when people stand most frequently. It must not be consumed after the evening meal or less than 3 hours before bedtime.

Since it is unknown if this medication will work longer than 2 weeks, it must be taken only if symptoms continue to get better during treatment. Do not take this medication for longer than 2 weeks unless recommended by your doctor. Learn how to monitor your blood pressure and share the results with your doctor. Tell your doctor if your condition does not improve or if it worsens.

What are the side effects of Droxidopa?

  • Dizziness
  • Headache
  • Nausea
  • Tired feeling
  • Falls
  • Fainting

What are the precautions in taking Droxidopa?

  • This product may contain an inactive ingredient that can cause allergic reactions. Let your doctor know if you have any allergies.
  • Do not drive or do any activity that needs your full alertness. This drug makes you drowsy or dizzy. Perform activities until you know how this drug will affect you.
  • Before using this, consult first your doctor if you are pregnant or breastfeeding women. This medicine should only be used when needed.
  • This medicine increases your blood pressure. Raise the head of your bed to lessen the risk of high blood pressure that happens when lying down. This type of condition is known as supine hypertension.
  • Alcohol can make you dizzier. Limit alcoholic beverages while having this treatment.
  • Before having surgery, inform your doctor about all the products you use including non-prescription drugs, prescription drugs, vitamins, food supplements, or herbal products.