What condition does Degarelix treat?

Degarelix is used for the treatment of advanced prostate cancer. This condition can spread to any part of the body and is commonly spreading to the bones and lymph nodes.

This medication is not a cure but this may help to slow the growth of cancer cells. Most types of prostate cancer need the male hormone testosterone to spread and grow.

Degarelix is a sterile lyophilized powder for injection. It is a synthetic linear decapeptide amide that has seven unnatural amino acids. This comes as a vial for subcutaneous administration. The Food and Drug Administration (FDA) has approved this medication.

How does Degarelix work?

Degarelix aggressively prevents GnRH receptors in the pituitary gland. It prevents the discharge of luteinizing hormone (LH). It also prevents the release of follicle-stimulating hormones. Reduced LH suppresses testosterone release. Wherein, it slows the development and lessens the size of prostate cancers.

What is the recommended dosage for Degarelix?

Degarelix is to be injected under the skin in the stomach area. It must be away from the ribs and waistline. This medication is usually injected once every 28 days.

The first dose is given as two injections. The following doses are given as one injection.  To help you remember, mark your calendar to keep track of when to schedule the next dose.

The first time you receive this medication, you will be given two injections. At your monthly follow-up visits, you will receive only one injection. You will need frequent medical tests. This medication might affect the results of some medical assessments. Inform any doctor who treats you that you are having this medication.

What are the side effects of Degarelix?

Common side effects:

  • Chills
  • Back or joint pain
  • Fatigue
  • Tiredness
  • Dizziness
  • Fever
  • Nausea
  • Weakness
  • Insomnia
  • Headache
  • Increased sweating
  • Weight gain
  • Constipation
  • Injection site reactions (redness, swelling, or pain)

If these side effects continue or get worse, call your doctor right away.

What are the precautions in taking Degarelix?

  • While having this treatment, makes sure the injection site is free from any pressure. It is more likely pressure from belts, waistbands, or other types of clothing.
  • Change the injection site each time to lessen the discomfort after the injection.
  • Call for medical help if there are signs of an allergic reaction.
  • This is not usually used in women. You should also not use this in pregnant or breastfeeding women.
  • Before having this medication, tell your doctor if you are taking other medications.
  • This drug may make you feel dizzy. Do not drive or use any machinery.
  • This medicine may reduce bone mineral density when used for a long period. A low bone mineral density could cause osteoporosis or weak bones. Ask your doctor if you have any questions about this.
  • Do not receive any kind of vaccination or immunization without approval from your doctor while having treatment with this medicine.
  • Drinking alcoholic beverages must be avoided completely or kept to a minimum. You should discuss this with your doctor.
  • Avoid contact sports or activities that could cause injury.