Angeliq (Drospirenone and Estradiol)

General Information

Angeliq (Drospirenone and Estradiol) is used to reduce menopause symptoms. This helps to reduce episodes of flushing and sweating of the upper body and face. It is commonly called hot flashes. This may also be used for the treatment of dryness, burning, and itching around the vagina. These symptoms occur when a woman’s body no longer makes the usual amount of female hormone (estrogen). 

How does Angeliq (Drospirenone and Estradiol) work?

Oestrogen (in the form of estradiol) can be given as a supplement to replace the falling levels in the body. It helps to decrease these distressing symptoms of the menopause. This is known as hormone replacement therapy (HRT). It is usually only required for short-term relief from menopausal symptoms

Progestogen (in the form of Drospirenone) is needed as part of HRT for women who have not had a hysterectomy. This is because in women with an intact womb, it stimulates the progress of the womb lining. In which it leads to endometrial cancer if the development is unopposed. A progestogen is given to oppose estrogen’s effect on the womb lining. This lessens the risk of cancer, though it does not eliminate this risk entirely. This is known as combined HRT.

This medication is a continuous form of combined HRT. Each tablet contains both estradiol and drospirenone. This type of HRT does not produce a monthly bleed and so is more suitable for women whose periods have already stopped 

Why use Angeliq (Drospirenone and Estradiol)?

Angeliq Tablets is a combination of two female hormones; an estrogen (estradiol) and a progestin (Drospirenone). Estradiol is a naturally occurring form of estrogen and Drospirenone is a synthetic form of progesterone.

Progestin is added to estrogen replacement therapy to decrease the risk of cancer of the uterus. A woman who has had her uterus removed does not need progestin. It should not be treated with this combination of medication.

This drug is in a tablet form for oral administration. Each tablet has the strength of 0.25mg. The Food and Drug Administration (FDA) has approved this medication.

How to use Angeliq (Drospirenone and Estradiol)?

This is usually taken once a day by mouth. Take it exactly as it is prescribed. To help you remember, take it at the same time every day. You may take this with or without prescription and food. The dosage is based on your condition and response.

What are the side-effects of Angeliq (Drospirenone and Estradiol)?

  • Mood changes
  • Headache
  • Breast pain
  • Changes in your menstrual periods
  • Vaginal itching or discharge
  • Diarrhea
  • Nausea
  • Stomach pain

Warnings and Precautions

  • Inform your doctor if you have any allergies as well as medical history or current medications.
  • Talk with your doctor the risks and benefits of this drug first.
  • Keep this and all of your other medications away from the reach of children.