Valsartan

Valsartan

Valsartan is indicated to treat highblood pressure or also known as hypertension. It is a long-term force of theblood against your artery walls is high enough that it may eventually causehealth problems like heart disease. Blood pressure is determined both by theamount of blood your heart pumps. It is also determined by the amount ofresistance to blood flow in your arteries. The more blood your heart pumps andthe narrower your arteries, the higher your blood pressure. You can have thiscondition for years without any symptoms. Hypertension generally develops overyears and it affects nearly everyone eventually.

This medication may also be usedto treat heart failure. This condition is also known as congestive heartfailure. It occurs when your heart muscle does not pump blood as well as itshould. Heart failure can be ongoing or it may start suddenly. Some signs andsymptoms may include:

  • Fatigue and weakness
  • Shortness of breath when you exert yourself orwhen you lie down
  • Rapid or irregular heartbeat
  • Swelling in your legs, ankles, and feet
  • Persistent cough or wheezing
  • Reduced ability to exercise
  • Swelling of your abdomen
  • Increased need to urinate
  • Lack of appetite and nausea
  • Very rapid weight gain from fluid retention
  • Sudden or severe shortness of breath
  • Chest pain if your heart failure is caused by aheart attack

Valsartan belongs to the class ofmedications called angiotensin receptors blockers (ARBs). This relaxes bloodvessels so that blood can flow more easily. Lowering high blood pressure helpsprevent heart attacks, strokes, and kidney problems. In heart failure, thisdrug lowers the chance of having to go to the hospital for heart failure. Thisis a prescription approved by the Food and Drug Administration (FDA). Valsartanis supplied as an aqueous solution for oral use. It is formulated at aconcentration of 4 mg/mL. Each contains Valsartan as an active ingredient whichis slightly soluble in water and soluble in methanol and ethanol.

Howdoes Valsartan work?

Valsartan works by blockingreceptors in the body known as angiotensin II receptors. This prevents theaction of a hormone called angiotensin II. It is involved in regulating blood pressure andfluid balance. It has two main actions that cause the blood vessels to narrowand the kidneys to retain salt and water. This drug blocks the receptors thatangiotensin II acts on and so prevents its actions. The main result of this isthat the peripheral blood vessels are allowed to widen. It means that there aremore space and less resistance in these blood vessels. This is the mainmechanism by which the pressure in the blood vessels is lowered. Blocking the actions of angiotensin IIalso increases the amount of fluid removed from the blood by the kidneys. This lessensthe quantity of fluid in the blood vessels, which similarly decreases the pressureand resistance in the blood vessels. The combined effect of these changes is tolower the blood pressure.

In treating heart failure, thismedication reduces the workload of the heart. It also has been shown to improvesurvival in people who have these problems following a heart attack.

Howto use Valsartan?

Valsartan is to be taken by mouthusually once or twice a day. You may take the medication with or without a mealas directed by your doctor. If you are using the liquid form of thismedication, shake the bottle well for at least 10 seconds before each dose. Measurecarefully the dosing using a special measuring spoon. Do not use a household spoonbecause you may not get the correct dose. The prescribed dosage is based onyour medical condition and response to the treatment. You must take thismedication exactly as it is given by your doctor. You should not take less or moreoften than the prescription. Your doctor may direct you to start at a lowerdose and eventually increase it. Do not suddenly stop taking Pindolol withoutthe consent of your doctor. It is important to continue taking this even if youfeel well. If you missed a dose, take it as soon as you remember it. If it isalmost time for your next dose, skip the missed dose and continue your regulardosing schedule. Do not double the dose to make up for the missed dose. Letyour doctor know if your condition worsens or does not improve.

Whatare the side effects of Valsartan?

  • Dizziness
  • Headache
  • Abdominal pain
  • Fatigue
  • Diarrhea
  • Low blood pressure
  • Joint or back pain
  • Cough
  • High potassium
  • Increased blood creatinine

Call for emergency medical helpif you have signs of an allergic reaction such as:

  • Hives
  • Trouble breathing
  • Swelling of your face, lips, tongue, and throat

Warningsand Precautions

  • Before using Valsartan, let your doctor know ifyou any medical history especially of liver disease or loss of too much body waterand minerals.
  • Inform your doctor if you ever had an allergicreaction to this medication. Tell also if you have any allergies. This drug maycontain an inactive ingredient that causes an allergic reaction.
  • This medication may increase your potassiumlevels. Before using any potassium supplements, consult your doctor first.
  • Let your doctor know if you have any currentmedications including herbal remedies or vitamins.
  • Weariness and dizziness may occasionally occurwhile having this treatment with blood pressure-lowering drugs. Dizziness canbe relieved by lying down until the symptoms pass. If you experience this, cautionis needed when driving or operating machinery.
  • This product is not recommended for triple therapyin combination with both ACE inhibitors and beta-blocker when treating heartfailure.

This medication should be usedwith caution in people:

  • Who are having kidney dialysis and who have had akidney transplant
  • With severe heart failure
  • With mild to moderately decreased liver function
  • With heart valve disease and heart diseasecharacterized by thickening of the internal heart muscle and a blockage insidethe heart

This should not be used in:

  • People with severe liver problems
  • People with failure of the normal flow of bile fromthe liver to intestines
  • Pregnancy
  • Breastfeeding