Targretin (Bexarotene) is used to treat cutaneous T-cell lymphoma (CTCL). It is a skin problem from a certain type of cancer. CTCL is a kind of condition in which certain cells of the body’s lymph system called T-cells. It becomes cancerous and it affects the skin.
How do Targretin (Bexarotene) Capsules work?
Retinoids are medications that are relatives of vitamin A. It controls normal cell development, cell differentiation, and cell death during embryonic development and in certain tissues later in life. It effects on the cells are controlled by receptors on the nucleus of each cell (nuclear receptors). Retinoids are relatively new types of anti-cancer drugs.
There are two main classes of retinoid nuclear receptors: retinoid-X-receptors (RXR) and retinoic acid receptors (RAR). There are also subtypes within each class. Each one of these types of receptors has different purposes in different tissues. The different retinoid remedies work by binding to different receptors. In which affects cell development and difference.
Why use Targretin (Bexarotene) Capsules?
Targretin Capsule contains Bexarotene as an active ingredient. This belongs to the class of medications known as retinoids that selectively activate retinoid X receptors (RXRs). These retinoid receptors have biologic action different from that of retinoic acid receptors. Each soft gelatin capsule contains 75 mg of Bexarotene for oral administration. The Food and Drug Administration (FDA) approved this.
How to use Targretin (Bexarotene) Capsules?
Take this medication exactly as prescribed. Your doctor will give a suitable dose for you.
The recommended dose for this treatment is 4-10 capsules to be taken once a day. Take it at the same time each day with a meal. You may take it before, during, or immediately after eating. The medicine should be swallowed as a whole, do not break or chew it.
What are the side-effects of Targretin (Bexarotene) Capsules?
- Changes in vision
- Swelling (feet or hands)
- Fatigue or extreme weakness
- Abdominal pain
- Chills (flu symptoms)
- Rash, dermatitis or dry skin
- Sensitivity to light
If these side effects persist or worsen, call for medical help right away.
Warnings and Precautions
- This medication should not be used in adolescents or children.
- If you are pregnant or breastfeeding women, consult your doctor first before using this treatment.
- Let your doctor know if you have any current medications (vitamins/herbal supplements)
- You should not share this to others without letting them consult a doctor.
- Keep this way from heat/moisture.