Orilissa (Elagolix) is used to help relieve moderate to severe pain. This is used by women with a condition called endometriosis. It is a kind of condition that is often painful in which tissue that normally lines the inside of the uterus. It most commonly involves your ovaries, the tissue lining your pelvis, and fallopian tubes. This condition may cause symptoms such as:
- Pain during or after sex
- Painful, heavy or irregular menstrual periods
How does Orilissa (Elagolix) work?
Orilissa (Elagolix) is an orally-administered and a non-peptide small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist. It inhibits endogenous GnRH signaling by binding competitively to GnRH receptors in the pituitary gland. Administration of this drug results in dose-dependent suppression of luteinizing hormone (LH). It also results in follicle-stimulating hormone (FSH). In which it leads to decreased blood concentrations of the ovarian sex hormones, progesterone, and estradiol.
Why use Orilissa (Elagolix)?
Orilissa Tablets contains Elagolix as an active ingredient. It is a white to off white to light yellow powder. It is freely soluble in water. In the year 2018, the Food and Drug Administration (FDA) approved this medication. This is available as tablets for oral use that has the strength of 150mg.
How to use Orilissa (Elagolix)?
This medication is usually taken once or twice a day. Take it by mouth with or without food or as prescribed by your doctor.
The dosage and length of treatment are based on your condition, response, and other drugs you may be taking. This medication is usually taken for up to 6 months or up to 24 months.
Use this regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not suddenly stop taking this medication it may worsen your condition.
What are the side-effects of Orilissa (Elagolix)?
- Hot flushes or night sweats
- Missed menstrual periods
- Joint pain
- Mood changes
Warnings and Precautions
- This is not recommended for use during pregnancy. This may harm an unborn baby. If you become pregnant while taking this medication, tell your doctor right away.
- It is unknown if it passes into breast milk. Consult your doctor first before breastfeeding.
- Do not share this with others who have the same symptoms as yours.
- Tell also to your doctor about the medical history you have especially of liver problems or osteoporosis.
- Keep this at a dry and clean place to avoid contaminations.