Nitazoxanide is used to treat diarrhea caused by Giardia or Cryptosporidium. These conditions are sometimes called Traveler’s diarrhea. It is a kind of condition that may be also caused by a certain parasite infection of the intestines. This medication is used in adults and children who are at least 1 year old.
How does Nitazoxanide work?
Nitazoxanide works by stopping the growth of certain protozoa that cause diarrhea. The activity of this drug is believed to be due to interference with the pyruvate: ferredoxin oxidoreductase enzyme-dependent electron transfer reaction. It is vital to anaerobic energy breakdown. Experts have presented that the PFOR enzyme from Giardia lamblia directly lessens Nitazoxanide. It is by transferring electrons in the absence of ferredoxin. The DNA derived PFOR protein sequence of the Cryptosporidium parvum appears to be similar to that of Giardia lamblia.
Why use Nitazoxanide?
Nitazoxanide is an artificial antiprotozoal agent for oral administration. It is a light yellow crystalline powder. This is considered as the first drug to treat cryptosporidium and effective in treating diarrhea. Nitazoxanide is available in the strength of a 500 mg tablet. The Food and Drug Administration (FDA) has approved this medication.
How to use Nitazoxanide?
Nitazoxanide is to be taken bymouth with a full glass of water. It is usually taken every 12 hours for 3days. Each dose is to be taken with food as directed by your doctor. Don’tforget to take it at the same time and in the same way each day. Follow theinstructions of your doctor very carefully for the best benefit from the drug.
The recommended dosage is basedon your medical condition, age, and response to it. You should not take more orless than the prescription. Let your doctor know if your condition gets worseor does not improve.
What are the side effects of Nitazoxanide?
- Abdominal pain
- Eye discoloration
- Discolored urine
- Severe dizziness
- Trouble breathing
- Allergic reaction (rash, swelling of the face,tongue, throat)
If these side effects persist orworsen, call your doctor right away.
Warnings and Precautions
- Inform your doctor if you have any allergies,medical history or current medications.
- While taking this drug, limit your alcoholbeverages.
- This may make you feel dizzy. Avoid driving, usingmachinery, or perform some activity that needs your alertness.
- Consult first your doctor if you are pregnant orbreastfeeding women.
- Keep this away from the direct sunlight or heat.