Indomethacin

Indomethacin

Where is Indomethacin used?

Indomethacin is used in adults to relieve pain and inflammation in a wide range of conditions including:

  • Osteoarthritis 
  • Rheumatoid arthritis 
  • Acute gout
  • Dysmenorrhea

This medicine is known as a nonsteroidal anti-inflammatory drug (NSAID). This blocks your body’s production of certain natural substances that cause inflammation. The effect of Indomethacin helps to decrease swelling and pain. 

How does Indomethacin work?

Indomethacin blocks the action of a substance in the body called cyclo-oxygenase (COX). COX is involved in the production of various chemicals in the body. Some of which are known as prostaglandins. These are produced by the body in response to injury and certain diseases and conditions. It causes inflammation, pain, and swelling. Indomethacin blocks the creation of these prostaglandins and as a result, this is effective at decreasing pain and inflammation. 

Indomethacin provides prolonged pain relief so this is to be taken exactly as directed by your doctor. The capsules must be swallowed whole to avoid damaging the modified-release action.

How is Indomethacin taken?

This is to be taken by mouth usually 2 to 3 times a day or as directed by your doctor. Do not lie down for at least 10 minutes after taking this drug. If stomach upset happen, take it with food, antacid, or milk. The dosage is based on your medical condition and response to the treatment. To lessen the risk of stomach bleeding and other side effects, take this at the lowest effective dose for the shortest possible time. Do not increase your dose or use this drug more often or for longer than the prescription. Remember to take this prescription in the same way and at the same time each day. 

Before you notice the full benefits, it may take up to 4 weeks when this drug is taken regularly in certain conditions. If you are taking this drug as needed basis, remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well. Let your doctor know if your condition does not improve. If you missed a dose, call your doctor for instructions. Do not twice the dosage to make up for the missed dose. 

What are the possible side effects of Indomethacin?

  • Loss of appetite
  • Drowsiness
  • Light-headedness 
  • Diarrhea
  • Indigestion
  • Constipation
  • Vomiting
  • Dizziness
  • Headache
  • Nausea

What are the precautions in using Indomethacin?

  • Indomethacin may cause dizziness that may affect your capacity to operate machinery or drive safely. Do not operate machinery or drive until you know how this medicine affects you and you are sure it won’t affect your performance.
  • The lowest effective dose of this medicine will be given by your doctor. It may be for the shortest possible time needed to relieve your symptoms. This is to minimize the chances of any side effects. It is important not to exceed the prescribed dose.
  • Certain medicines should not be used during breastfeeding or pregnancy. Inform your doctor if you are planning a pregnancy or pregnant, before using any medication
  • Let your doctor if you ever had an allergic reaction to this drug. Tell also if you have any allergies. This medication may contain an ingredient that causes an allergic reaction. 
  • Use this with caution in people with a history of disorders that affects the stomach, who have inflammatory bowel disease, decreased kidney or liver function, heart failure, or high blood pressure.