Acarbose

Acarbose

Acarbose is used for thetreatment of type 2 diabetes mellitus. It is also known asnon-insulin-dependent diabetes mellitus or adult-onset diabetes. According topharmacological studies, this develops a glycemic mechanism while lessening thecirculating insulin levels. This also improves the sensitivity to insulin inmuscle. This medication is used along with a proper diet and exercise programto control high blood pressure. Proper control of diabetes may lower your riskof heart attack and stroke. Controlling high blood pressure helps also prevent:

  • Loss of limbs
  • Kidney damage
  • Blindness
  • Nerve problems
  • Sexual function problems

Type 2 diabetes mellitus is achronic condition. That it affects the way your body metabolizes sugar. Glucoseor sugar is an important source of fuel for your body. With this condition,your body either resists the effects of insulin or doesn’t produce enoughinsulin to maintain normal glucose levels. There’s no cure for type 2 diabetesmellitus but losing weight, eating well, and exercising can help manage the disease.If diet and exercise are not enough to manage your blood sugar well, you mayalso need diabetes medications or insulin therapy. Signs and symptoms of type 2diabetes mellitus may include:

  • Frequent urination
  • Increased thirst
  • Unintended weight loss
  • Increased hunger
  • Blurred vision
  • Fatigue
  • Frequent infections
  • Slow-healing sores
  • Areas of darkened skin usually in the armpits andneck

Acarbose is a prescription approvedby the Food and Drug Administration (FDA). This is supplied as a tablet fororal use. Each tablet has Acarbose as an active ingredient. It is an oralalpha-glucosidase inhibitor that slows the breakdown and absorption of carbohydratesfrom the foods you eat. It is also known as a man-made oligosaccharide designedto slow down the actions of alpha-amylase and alpha-glucosidase. This effecthelps lessen your blood sugar rises after a meal. Acarbose is available in thedosage forms of 25 mg, 50 mg, and 100 mg.

Howdoes Acarbose work?

If you have type 2 diabetesmellitus, your body doesn’t use the hormone insulin normally. It can’t controlthe amount of sugar or glucose in the blood.

Acarbose slows the breakdown andabsorption of sugars and starches in the gut. It is by preventing the action ofenzymes in the intestine that would usually break down the sugars and starches thatyou eat. It is also into molecules that are small enough to be absorbed intothe bloodstream. It has the most effect on an enzyme called sucrose whichnormally breaks down a type of sugar called sucrose.

Howto use Acarbose?

The prescribed dosage is based onyour medical condition and response to the treatment. You musttake this medication exactly as it is given by your doctor. You should not takeless or more often than the prescription. Your doctor may direct you to startat a lower dose and eventually increase it. Let your doctor know if your conditionworsens or does not improve.

Acarbose is to be taken by mouthusually three times a day or as directed by your doctor. This medication is tobe taken with meals to delay the breakdown of sugars and starches in the gut. Thisalso slows down their absorption into the blood.  Do not suddenly stop taking Acarbose withoutthe consent of your doctor. It is important to continue taking this even if youfeel well. To help you remember, take it at the same time and in the same wayeach day. Swallow the tablet as a whole with a full glass of water. Do notbreak, chew, or crush it. Drink plenty of fluids while having this treatment.Doing so may lessen the risk of certain side effects. If you missed a dose,take it as soon as you remember it. If it is almost time for your next dose,skip the missed dose and continue your regular dosing schedule. Do not doublethe dose to make up for the missed dose.

Whatare the side effects of Acarbose?

Common side effects:

  • Gas
  • Diarrhea
  • Upset stomach
  • Diarrhea
  • Skin rash or itching
  • Stomach pain in the first few weeks of treatmentas your body adjusts to the medication

Let your doctor know if you have rarebut very serious side effects of this medication such as:

  • Persistent nausea or vomiting
  • Unusual tiredness
  • Rectal bleeding
  • Severe stomach or abdominal pain
  • Dark urine
  • Diarrhea that is watery or bloody
  • Easy bruising
  • Yellowing eyes or skin

Get emergency medical help if youhave any signs of an allergic reaction such as:

  • Hives
  • Difficulty breathing
  • Swelling of your face, lips, tongue, or throat

Warningsand Precautions

  • Before taking Acarbose, tell your doctor if youhave any medical history especially of kidney or liver problems and intestinalor bowel problems.
  • You may experience dizziness or blurred vision dueto extremely low or high blood sugar. Do not drive or do any activity thatneeds alertness or clear vision.
  • Limit alcohol while having this treatment. It mayincrease your risk of developing low blood sugar.
  • While you are taking this drug, your doctor maywant to check your blood sugar level from time to time.
  • This medicine does not cause low blood sugar. However,if it is added to treatment with other antidiabetic medicines there is morechance of your blood sugar falling too low. If you experience hypoglycemia whilehaving this medication, it should be treated with glucose, not sucrose.
  • This may rarely affect your liver. For thisreason, this is not recommended that your liver function is monitored for thefirst 6-12 months of treatment with Acarbose.
  • Do not share this with others even if they have thesame symptoms as yours.
  • This is not recommended for use in pregnant or breastfeedingwomen.
  • This medication should not be used in:
  • People with a tendency to suffer from total orpartial blockages in the gut
  • People with ulceration in the bowel
  • Those with severely decreased liver or kidneyfunction
  • Those with a condition of hernias that may worsenas a result of increased gas formation in the gut